Canada Gazette, Part I, Volume 150, Number 25: GOVERNMENT NOTICES

June 18, 2016

(Erratum)

DEPARTMENT OF THE ENVIRONMENT

CANADIAN ENVIRONMENTAL PROTECTION ACT, 1999

Notice requiring the preparation and implementation of pollution prevention plans in respect of halocarbons used as a refrigerant

Notice is hereby given that the notice bearing the abovementioned title published as a supplement to the Canada Gazette, Part I, Vol. 150, No. 21, Saturday, May 21, 2016, on page 6, contained an error.

Subsection 6(1) should have read as follows:

(1) For a person or class of persons subject to the Notice on the date of its publication in the Canada Gazette, Part I, the Minister requires that the plan be implemented no later than November 20, 2018.

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DEPARTMENT OF ENVIRONMENT AND CLIMATE CHANGE

CANADIAN ENVIRONMENTAL PROTECTION ACT, 1999

Notice of intent to amend the Non-domestic Substances List under subsection 66(2) of the Canadian Environmental Protection Act, 1999

Notice is hereby given that the Minister of Environment and Climate Change intends to amend the Non-domestic Substances List, pursuant to subsection 66(2) of the Canadian Environmental Protection Act, 1999. (see footnote 1)

Public comment period

Any person may, within 60 days of publication of this Notice, indicate if any of the substances are in the Canadian marketplace (i.e. being imported into or manufactured in Canada) in quantities that exceed 100 kg in a calendar year. Substances found to be in the Canadian marketplace will be considered for delayed removal from the Non-domestic Substances List. All comments must cite the Canada Gazette, Part I, and the date of publication of this Notice and be sent to the Executive Director, Program Development and Engagement Division, Environment and Climate Change Canada, Gatineau, Quebec K1A 0H3, 819-938-5212 (fax), eccc.substances.eccc@canada.ca (email).

In accordance with section 313 of the Canadian Environmental Protection Act, 1999, any person who provides information in response to this Notice may submit with the information a request that it be treated as confidential.

GEORGE ENEI
Assistant Deputy Minister
Science and Technology Branch

On behalf of the Minister of Environment and Climate Change

ANNEX

1. Part I of the Non-Domestic Substances List (see footnote 2) is proposed to be amended by deleting the following:

COMING INTO FORCE

2. This Order would come into force on the day on which it is published in the Canada Gazette.

EXPLANATORY NOTE

(This explanatory note is not part of the Notice of Intent to amend the Non-domestic Substances List.)

Description

The Notice of Intent is an opportunity for the public to comment on proposed amendments to the Non-domestic Substances List (NDSL), pursuant to subsection 66(2) of the Canadian Environmental Protection Act, 1999 (CEPA), to delete 741 substances from this List.

Background

The NDSL is an inventory of substances new to Canada, but also recognized as being in use internationally. The NDSL is based on the United States Environmental Protection Agency (U.S. EPA) Toxic Substances Control Act (TSCA) Chemical Substances Inventory. On a semi-annual basis, substances that have been on the public portion of the U.S. EPA TSCA Chemical Substances Inventory for a minimum period of one year and that are not subject to risk management controls in the United States or in Canada are added to the NDSL. Substances on the NDSL are subject to the New Substances Notification Regulations (Chemicals and Polymers). However, they are subject to lesser information requirements (e.g. higher reporting thresholds) than new substances that are not listed.

Since the establishment of the NDSL, risk management controls have been developed in the United States on certain substances found on the NDSL. Although controlled in the United States, these substances continue to be subject to lesser reporting requirements in Canada because they are on the NDSL.

Project scope

Environment and Climate Change Canada initiated a review of substances on the NDSL to assess if risk management controls had been developed for these substances in the United States. Moving forward, a bi-annual review will enable the Government of Canada to identify substances that may potentially be of concern and to propose their removal from the NDSL. Risk management controls imposed by other jurisdictions can signal potential concerns in Canada; therefore, more stringent reporting requirements are needed for these substances (i.e. the same requirements as new substances not listed on the NDSL).

Project outcome

Under the current review, a total of 741 substances were identified as being subject to risk management controls in the United States. Therefore, it is proposed to delete these 741 substances from the NDSL. Resulting amendments to the NDSL are expected to improve the protection of Canadians and their environment, while providing greater regulatory alignment with the United States.

Consultation

Consultations were held with key stakeholders in 2015 and they expressed general support for this initiative.

Next steps

Within 60 days of publication of the Notice, any person may submit comments or identify whether any of the 741 substances are currently in the Canadian marketplace in quantities that exceed 100 kg in a calendar year. Comments will be taken into consideration during the development of the final Order, and identified stakeholders with current business interests in these chemicals (i.e. current importers or manufactures) will be engaged to facilitate a transition to the new reporting requirements. For example, delayed removal will be considered for substances in the Canadian marketplace should additional time be required to ensure continued compliance with the New Substances Notification Regulations (Chemicals and Polymers). The final Order will be published in the Canada Gazette, Part I.

Should future bi-annual reviews identify substances of potential concerns, a Notice of Intent would also be published in the Canada Gazette, Part I, for a 60-day public consultation, prior to amending the NDSL.

Amendments to the NDSL are not in force until the Order is published in the Canada Gazette, Part I.

Contact information

Please send your feedback, suggestions, or questions to the Substances Management Information Line:

Telephone: 1-800-567-1999 (toll-free in Canada)
819-938-3232 (outside of Canada)
Fax: 819-938-5212
Email: eccc.substances.eccc@canada.ca

For additional information or documentation regarding the Regulations, please visit the New Substances program Web site at www.ec.gc.ca/subsnouvelles-newsubs.

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DEPARTMENT OF THE ENVIRONMENT

DEPARTMENT OF HEALTH

CANADIAN ENVIRONMENTAL PROTECTION ACT, 1999

Publication of final decision after screening assessment of 52 azo acid dyes specified on the Domestic Substances List (paragraphs 68(b) and 68(c) or subsection 77(6) of the Canadian Environmental Protection Act, 1999)

Whereas 47 of the 52 azo acid dyes identified in the annex below are substances on the Domestic Substances List identified under subsection 73(1) of the Canadian Environmental Protection Act, 1999;

Whereas a summary of the screening assessment conducted on five azo acid dyes pursuant to paragraphs 68(b) and (c), and pursuant to section 74 of the Act for the remaining 47 azo acid dyes is annexed hereby;

Whereas the substances bearing CAS RN (see footnote 3) 71720-89-3, CAS RN 83027-51-4, CAS RN 83027-52-5, CAS RN 90218-20-5, CAS RN 90459-02-2 and CAS RN 114910-04-2 are currently subject to the Significant New Activity provisions under subsection 81(3) of the Act;

And whereas it is concluded that the 52 azo acid dyes do not meet any of the criteria set out in section 64 of the Act;

Notice therefore is hereby given that the Minister of the Environment and the Minister of Health (the ministers) propose to take no further action on five substances at this time.

Notice is further given that the ministers propose to take no further action on the remaining 47 substances at this time under section 77 of the Act;

Notice is furthermore given that, pursuant to subsection 87(3) of the Act, the Minister of the Environment intends to amend the Domestic Substances List such that substances bearing CAS RN 71720-89-3, CAS RN 83027-51-4, CAS RN 83027-52-5, CAS RN 90218-20-5, CAS RN 90459-02-2 and CAS RN 114910-04-2 are no longer subject to the Significant New Activity provisions under subsection 81(3) of the Act.

CATHERINE MCKENNA
Minister of the Environment
JANE PHILPOTT
Minister of Health

ANNEX

Summary of the Screening Assessment of Certain Azo Acid Dyes

Pursuant to section 68 or 74 of the Canadian Environmental Protection Act, 1999 (CEPA), the Minister of the Environment and the Minister of Health have conducted a screening assessment on 52 azo acid dyes. These substances constitute a subgroup of the Aromatic Azo and Benzidine-based Substance Grouping being assessed as part of the Substance Groupings Initiative of the Government of Canada's Chemicals Management Plan based on structural similarity and applications. Substances in this Grouping were identified as priorities for assessment as they met categorization criteria under subsection 73(1) of CEPA and/or were considered as a priority based on other human health concerns.

The Chemical Abstracts Service Registry Number (CAS RN), Domestic Substances List (DSL) name and Colour Index (C.I.) generic name or common name of the 52 azo acid dyes are presented in the following table.

Identity of 52 Azo Acid Dyes in the Aromatic Azo and Benzidine-based Substance Grouping
CAS RN DSL name C.I. name or common name
587-98-4 Benzenesulfonic acid, 3-[[4(phenylamino)phenyl]azo]-, monosodium salt Metanil Yellow
633-96-5
(see note †)		 Benzenesulfonic acid, 4-[(2-hydroxy-1-naphthalenyl)azo]-, monosodium salt Orange II
915-67-3
(see note †)		 2,7-Naphthalenedisulfonic acid, 3-hydroxy-4-[(4-sulfo-1-naphthalenyl)azo]-, trisodium salt Amaranth
1934-21-0
(see note †)		 1H-Pyrazole-3-carboxylic acid, 4,5-dihydro-5-oxo-1-(4-sulfophenyl)-4-[(4-sulfophenyl)azo]-, trisodium salt Tartrazine
2611-82-7
(see note †)		 1,3-Naphthalenedisulfonic acid, 7-hydroxy-8-[(4-sulfo-1-naphthalenyl)azo]-, trisodium salt New Coccine
3071-73-6 1-Naphthalenesulfonic acid, 8-(phenylamino)-5-[[4-[(5-sulfo-1-naphthalenyl)azo]-1-naphthalenyl]azo]-, disodium salt Acid Black 24
3351-05-1 1-Naphthalenesulfonic acid, 8-(phenylamino)-5-[[4-[(3-sulfophenyl)azo]-1naphthalenyl]azo]-, disodium salt Acid Blue 113
3761-53-3 2,7-Naphthalenedisulfonic acid, 4-[(2,4-dimethylphenyl)azo]-3-hydroxy-, disodium salt Ponceau MX
6262-07-3 2-Naphthalenesulfonic acid, 6-hydroxy-5-[[4-[[4-(phenylamino)-3-sulfophenyl]azo]-1-naphthalenyl]azo]-, disodium salt Acid Black 26
6507-77-3 1,3-Naphthalenedisulfonic acid, 7-hydroxy-8-[[4-[1-[4-[(4-hydroxyphenyl)azo]phenyl]cyclohexyl]phenyl]azo]-, disodium salt Acid Orange 33
15792-43-5 2,7-Naphthalenedisulfonic acid, 5-(acetylamino)-3-[(4-dodecylphenyl)azo]-4-hydroxy-, disodium salt Acid Red 138
25317-22-0 1-Naphthalenesulfonic acid, 3-[[4-(benzoylethylamino)-2-methylphenyl]azo]-4-hydroxy- Acid Red 6
29706-48-7 Benzenesulfonic acid, 3-[[[4-(2-benzothiazolylazo)-3-methylphenyl]ethylamino]methyl]- N/A
35342-16-6 7-Benzothiazolesulfonic acid, 2-[4-[(hexahydro-2,4,6-trioxo-5-pyrimidinyl)azo]phenyl]-6-methyl-, monolithium salt N/A
51988-24-0 Benzenesulfonic acid, 3-[[4-[(4-hydroxy-3-methylphenyl)azo]-3-methoxyphenyl]azo]-, monolithium salt N/A
52236-73-4
(see note †)		 Benzenesulfonic acid, 4-[(5-amino-3-methyl-1-phenyl-1H-pyrazol-4-yl)azo]-2,5-dichloro-, monolithium salt N/A
62133-79-3 2-Naphthalenesulfonic acid, 5-[[4-[ethyl[(3-sulfophenyl)methyl]amino]phenyl]azo]-8-(phenylazo)-, disodium salt N/A
62133-80-6 2-Naphthalenesulfonic acid, 8-[[4-[ethyl[(3-sulfophenyl)methyl]amino]phenyl]azo]-5-(phenylazo)-, disodium salt N/A
67892-55-1 1-Naphthalenesulfonic acid, 5-[[4-[(2-chlorophenyl)azo]-6(or 7)-sulfo-1-naphthalenyl]azo]-8-(phenylamino)-, disodium salt N/A
68155-63-5 2,7-Naphthalenedisulfonic acid, 5-[[2,4-dihydroxy-5-[(4-nitrophenyl)azo]phenyl]azo]-4-hydroxy-3-[(2-hydroxy-3,5-dinitrophenyl)azo]-, disodium salt N/A
68555-86-2 Benzenesulfonic acid, 4-[[5-methoxy-4-[(4-methoxyphenyl)azo]-2-methylphenyl]azo]-, sodium salt Acid Orange 156
70210-05-8 2,7-Naphthalenedisulfonic acid, 3-[[2,4-bis(2-methylphenoxy)phenyl]azo]-4-hydroxy-5-[[(4-methylphenyl)sulfonyl]amino]-, disodium salt N/A
70210-06-9 Benzenesulfonic acid, 3-[[ethyl[4-[[4-[(3-sulfophenyl)azo]-1-naphthalenyl]azo]phenyl]amino]methyl]-, disodium salt N/A
70210-25-2 2,7-Naphthalenedisulfonic acid, 5-[[2,4-dihydroxy-5-[(2-hydroxy-3,5-dinitrophenyl)azo]phenyl]azo]-4-hydroxy-3-[(4-nitrophenyl)azo]-, disodium salt N/A
70210-34-3 2,7-Naphthalenedisulfonic acid, 5-[[2,4-dihydroxy-5-[[4-[(4-nitro-2-sulfophenyl)amino]phenyl]azo]phenyl]azo]-4-hydroxy-3-[[4-[(4-nitro-2-sulfophenyl)amino]phenyl]azo]-, tetrasodium salt N/A
71720-89-3 2-Naphthalenesulfonic acid, 5-[[4-(4-cyclohexylphenoxy)-2-sulfophenyl]azo]-6-[(2,6-dimethylphenyl)amino]-4-hydroxy-, disodium salt N/A
71873-51-3 Benzenesulfonic acid, 2,5-dichloro-4-[4-[[5-[[(dodecyloxy)carbonyl]amino]-2-sulfophenyl]azo]-4,5-dihydro-3-methyl-5-oxo-1H-pyrazol-1-yl]-, disodium salt N/A
72496-92-5 Naphthalenesulfonic acid, 5-[[2,4-dihydroxy-5-[[4-[(4-nitro-2-sulfophenyl)amino]phenyl]azo]phenyl]azo]-8-[[4-[(4-nitro-2-sulfophenyl)amino]phenyl]azo]-, trisodium salt NA
72828-67-2 1,3-Naphthalenedisulfonic acid, 7-hydroxy-8-[[4-[1-[4-[(4-hydroxyphenyl)azo]phenyl]cyclohexyl]phenyl]azo]-, potassium sodium salt N/A
72828-83-2 2,7-Naphthalenedisulfonic acid, 5-(benzoylamino)-3-[[2-(2-cyclohexylphenoxy)phenyl]azo]-4-hydroxy-, disodium salt N/A
72968-80-0 2-Naphthalenesulfonic acid, 5-[[4-[[(4-methylphenyl)sulfonyl]oxy]phenyl]azo]-8-[[4-[(4-nitro-2-sulfophenyl)amino]phenyl]azo]-, disodium salt N/A
72968-81-1 2-Naphthalenesulfonic acid, 8-[[4-[[(4-methylphenyl)sulfonyl]oxy]phenyl]azo]-5-[[4-[(4-nitro-2-sulfophenyl)amino]phenyl]azo]-, disodium salt N/A
72986-60-8 2-Naphthalenesulfonic acid, 5-[[4-[(4-nitro-2-sulfophenyl)amino]phenyl]azo]-8-[[4-[(phenylsulfonyl)oxy]phenyl]azo]-, disodium salt N/A
72986-61-9 2-Naphthalenesulfonic acid, 8-[[4-[(4-nitro-2-sulfophenyl)amino]phenyl]azo]-5-[[4-[(phenylsulfonyl)oxy]phenyl]azo]-, disodium salt N/A
75949-73-4 Benzenesulfonic acid, 4,4′-[methylenebis[4,1-phenyleneazo(4,5-dihydro-3-methyl-5-oxo-1H-pyrazole-4,1-diyl)]]bis[3-methyl-, disodium salt N/A
79234-36-9 2,7-Naphthalenedisulfonic acid, 5-(benzoylamino)-3-[[2-(4-cyclohexylphenoxy)phenyl]azo]-4-hydroxy-, disodium salt N/A
83006-48-8 Benzenesulfonic acid, 4-[4-[[3-[(ethylphenylamino)sulfonyl]-4-methylphenyl]azo]-4,5-dihydro-3-methyl-5-oxo-1H-pyrazol-1-yl]- N/A
83006-74-0 1-Naphthalenesulfonic acid, 8-(phenylamino)-5-[[4-[(5-sulfo-1-naphthalenyl)azo]-1-naphthalenyl]azo]-, ammonium sodium salt N/A
83006-77-3 1-Naphthalenesulfonic acid, 8-(phenylamino)-5-[[4-[(3-sulfophenyl)azo]-1-naphthalenyl]azo]-, ammonium sodium salt N/A
83027-51-4 1,7-Naphthalenedisulfonic acid, 6-[[2-(4-cyclohexylphenoxy)phenyl]azo]-4-[[(2,4-dichlorophenoxy)acetyl]amino]-5-hydroxy-, disodium salt N/A
83027-52-5 1,7-Naphthalenedisulfonic acid, 6-[[2-(2-cyclohexylphenoxy)phenyl]azo]-4-[[(2,4-dichlorophenoxy)acetyl]amino]-5-hydroxy-, disodium salt N/A
83221-60-7 1,6-Naphthalenedisulfonic acid, 4-[[4-[[1-hydroxy-6-(phenylamino)-3-sulfo-2-naphthalenyl]azo]-1-naphthalenyl]azo]-, ammonium sodium salt N/A
84559-92-2 2,7-Naphthalenedisulfonic acid, 3,3′-[azoxybis[(2-methoxy-4,1-phenylene)azo]]bis[4,5-dihydroxy-, tetralithium salt N/A
84962-50-5 Benzenesulfonic acid, 2,5-dichloro-4-[[2-(dibutylamino)-4-methyl-6-[[2-(4-sulfophenyl)ethyl]amino]-5-pyrimidinyl]azo]-, sodium salt N/A
85030-31-5 2,7-Naphthalenedisulfonic acid, 3-hydroxy-4-[[4-[[4-[(2-hydroxy-6-sulfo-1-naphthalenyl)azo]-2-methylphenyl]methyl]-3-methylphenyl]azo]-, sodium salt N/A
85136-25-0 2,7-Naphthalenedisulfonic acid, 3,3′-[azoxybis[(2-methoxy-4,1-phenylene)azo]]bis[4,5-dihydroxy-, lithium sodium salt N/A
85223-35-4 102616-51-3
(see note a)		 Benzoic acid, 3,3′-methylenebis[6-[[2,4-dihydroxy-5-[(4-sulfophenyl)azo]phenyl]azo]-, sodium salt N/A
90218-20-5 Benzenesulfonic acid, 5-amino-2,4-dimethyl-, diazotized, coupled with diazotized 2,4-, 2,5- and 2,6-xylidine and 4-[(2,4-dihydroxyphenyl)azo]benzenesulfonic acid, sodium salts N/A
90432-08-9 2,7-Naphthalenedisulfonic acid, 4-amino-5-hydroxy-, diazotized, coupled with diazotized 4-nitro-1,3-benzenediamine and resorcinol, potassium sodium salts N/A
90459-02-2 2,7-Naphthalenedisulfonic acid, 5-amino-4-hydroxy-3-[[6-sulfo-4-[(4-sulfo-1-naphthalenyl)azo]-1-naphthalenyl]azo]-, diazotized, coupled with diazotized 4-nitrobenzenamine and resorcinol, potassium sodium salts N/A
106028-58-4 2,7-Naphthalenedisulfonic acid, 6-amino-4-hydroxy-3-[[7-sulfo-4-[(4-sulfophenyl)azo]-1-naphthalenyl]azo]-, tetralithium salt N/A
114910-04-2 1-Naphthalenediazonium, 4-[[4-[(4-nitro-2-sulfophenyl)amino]phenyl]azo]-6-sulfo-, chloride, reaction products with formaldehyde and salicylic acid, ammonium sodium salts N/A

Abbreviation: N/A, not available.

Note †
This substance was not identified under subsection 73(1) of CEPA but was included in this assessment as it was considered a priority based on other human health concerns.

Note a
Two CAS RNs represent the same substance.

Azo acid dyes are not expected to occur naturally in the environment. No manufacture of any substance above the 100 kg/year reporting threshold has been reported in response to any recent surveys under section 71 of CEPA. Ten substances have been reported as having an import quantity above the 100 kg/year survey reporting threshold (during 2010).

Environment

All azo acid dyes are soluble in water, generally with solubilities well above 1 g/L. Given the import and use of 10 azo acid dyes in Canada above reporting thresholds, potential releases to the aquatic environment have been estimated. Considering the physical and chemical properties of these substances, when released to water, it is expected that the azo acid dyes may remain in the water column for relatively long periods of time due to their hydrophilicity, but will ultimately partition to suspended solids, sediments or soil particles via electrostatic interactions. Available experimental and modelled data regarding the abiotic and biotic degradation of the azo acid dyes indicate that these substances are likely to persist in water, sediment and soil. In anaerobic environments (i.e. anoxic layers of sediments), there is the potential for these substances to degrade to aromatic amines as a result of cleavage of the azo bond under anaerobic or reducing conditions.

Although there are limited experimental data available, information on the log octanol–water partition coefficients and fish bioconcentration factors indicates that these substances are not likely to bioconcentrate or bioaccumulate in aquatic organisms.

While all azo acid dyes are structurally related and are expected to have a common mode of action and environmental fate profile, review of physical-chemical and ecotoxicity data allowed them to be divided into subsets of monoazo, disazo and polyazo acid dyes for which aquatic toxicity levels were variable. Disazo acid dyes presented the highest levels of toxicity (effects at concentrations below 10 mg/L) while monoazo acid dyes showed lower toxicity (effects at concentrations below 100 mg/L). Polyazo substances were the least toxic to aquatic organisms (no effects below 100 mg/L). Soil toxicity data were limited, while sediment toxicity data were not available for these substances.

Risk quotient analyses were focused on exposure scenarios representing potential major environmental releases due to industrial activities involving azo acid dyes that may result in high levels of exposure of aquatic organisms. Predicted environmental concentrations were calculated for the aquatic environment for those substances identified in industrial formulation activities. Predicted environmental concentrations were not found to exceed the predicted no-effect concentrations for water.

Considering all available lines of evidence presented in this screening assessment, there is low risk of harm to organisms and the broader integrity of the environment from the azo acid dyes evaluated in this assessment. It is concluded that these 52 azo acid dyes do not meet the criteria under paragraph 64(a) or 64(b) of CEPA, as they are not entering the environment in a quantity or concentration or under conditions that have or may have an immediate or long-term harmful effect on the environment or its biological diversity or that constitute or may constitute a danger to the environment on which life depends.

Human health

Environmental media are not considered to be a significant source of exposure to azo acid dyes for the general population in Canada. Seventeen azo acid dyes (i.e. Acid Black 24, Acid Black 26, Acid Blue 113, Acid Orange 33, Acid Red 6, Acid Red 138, amaranth, new coccine, Orange II, tartrazine, substances bearing CAS RN 68155-63-5, CAS RN 70210-05-8, CAS RN 70210-06-9, CAS RN 70210-25-2, CAS RN 70210-34-3, CAS RN 71873-51-3 and CAS RN 84962-50-5) were indicated to be present in products in the Canadian marketplace that may lead to exposure of the general population to these substances. Exposure to amaranth and tartrazine occurs predominantly through food intake and the use of cosmetics, as well as through the use of certain non-prescription drugs (including natural health products regulated under the Food and Drug Regulations and the Natural Health Products Regulations) at the cosmetic-drug interface for tartrazine. Exposure to new coccine and Orange II is predominantly through the use of cosmetics. Exposure to the other 13 azo acid dyes is through contact with textile and/or leather products.

Margins between the upper-bounding estimates of oral exposure to amaranth from food and cosmetics and the critical health effect level from a chronic dietary study in rats are considered adequate to address uncertainties in the health effects and exposure databases.

Margins between the upper-bounding estimates of exposure to new coccine in certain cosmetics and the critical health effect levels are considered adequate to address uncertainties in the health effects and exposure databases.

Margins between the upper-bounding estimates of oral exposure to Orange II in lipstick and the critical health effect levels determined in oral studies in laboratory animals are considered adequate to address uncertainties in the health effects and exposure databases. Similarly, margins between the upper-bounding estimates of dermal exposure to Orange II in certain cosmetics and the no-observed-effect level from the dermal study in mice are considered adequate to address uncertainties in the health effects and exposure databases.

Margins between the upper-bounding estimates of exposure to tartrazine in food, cosmetics and non-prescription drugs at the cosmetic-drug interface and the critical health effect levels are considered adequate to address uncertainties in the health effects and exposure databases.

A range of critical effect levels from oral repeated-dose studies on azo acid dyes in this subgroup and relevant analogues was identified. However, no effects were observed in a chronic study in which mice received weekly applications to the skin of several azo acid dyes in this subgroup. These data were the basis for the risk characterization of 10 azo acid dyes lacking empirical data (i.e. Acid Red 138, Acid Orange 33, Acid Red 6, Acid Black 26, Acid Blue 113, Acid Black 24, substances bearing CAS RN 71873-51-3, CAS RN 84962-50-5, CAS RN 70210-05-8, and CAS RN 70210-06-9). Margins between upper-bounding estimates of oral exposure via mouthing of textile objects by infants and the range of oral critical effect levels were considered adequate to address uncertainties in the health effects and exposure databases. Margins between upper-bounding estimates of dermal exposure from direct and prolonged contact with textiles containing these dyes and the no-observed-effect level from the dermal study were considered adequate to address uncertainties in the health effects and exposure databases.

For three azo acid dyes (i.e. substances bearing CAS RN 68155-63-5, CAS RN 70210-25-2 and CAS RN 70210-34-3), the only potential exposure of the general population identified was from the use of leather products. As exposures to leather products are considered short term and intermittent and as available information does not indicate that azo acid dyes demonstrate high acute toxicity, the risk to human health for the general population is expected to be low.

For the remaining 35 azo acid dyes, available information did not identify potential for direct and prolonged exposure of the general population. Accordingly, risk for the general population to these substances is not expected.

Some of the azo acid dyes addressed in this assessment have effects of concern based on potential carcinogenicity. Whereas available information does not indicate a risk to human health for Canadians at current exposure levels to these substances, there may be a concern if exposures were to increase.

Based on the information presented in this screening assessment, it is concluded that the 52 azo acid dyes evaluated in this assessment do not meet the criteria for human health effects under paragraph 64(c) of CEPA, as they are not currently entering the environment in a quantity or concentration or under conditions that constitute or may constitute a danger in Canada to human life or health.

Overall conclusion

It is concluded that the 52 azo acid dyes evaluated in this assessment do not meet any of the criteria set out in section 64 of CEPA.

Although a risk to human health has not been identified for the general population of Canada at current levels of exposure, some substances in this assessment are recognized to have effects of concern based on their potential carcinogenicity. There may be a concern for human health if exposures of the general population of Canada to these substances were to increase in products available to consumers such as textiles and cosmetics.

Options on how best to monitor changes in the use profile of these substances are being investigated. Stakeholders will have the opportunity to provide feedback on a consultation document, describing potential options for information gathering or preventative actions, to be published once assessments for all of the Aromatic Azo and Benzidine-based Substances are completed.

The current screening assessment concludes that the potential ecological concern identified in the previous assessment of substances bearing CAS RN 71720-89-3, CAS RN 83027-51-4, CAS RN 83027-52-5, CAS RN 90218-20-5, CAS RN 90459-02-2 and CAS RN 114910-04-2 with respect to new uses as described in the screening assessment of 145 persistent, bioaccumulative and inherently toxic substances, published in April 2008, has changed. The current screening assessment concludes that these substances are no longer of concern to the environment, nor considered as having effects of concern. Consequently, the Minister of the Environment intends to rescind Significant New Activity provisions under subsection 81(3) of the Act.

The screening assessment for these substances is available on the Government of Canada's Chemical Substances Web site (www. chemicalsubstances.gc.ca).

DEPARTMENT OF THE ENVIRONMENT

DEPARTMENT OF HEALTH

CANADIAN ENVIRONMENTAL PROTECTION ACT, 1999

Publication of final decision after screening assessment of 275 substances specified on the Domestic Substances List (paragraphs 68(b) and (c) or subsection 77(6) of the Canadian Environmental Protection Act, 1999)

Whereas 271 of the 275 substances identified in annex II below are substances on the Domestic Substances List identified under subsection 73(1) of the Canadian Environmental Protection Act, 1999;

Whereas a summary of the final screening assessment conducted on 271 substances pursuant to section 74 and 4 substances pursuant to paragraphs 68(b) and (c) of the Act is annexed hereby;

And whereas it is concluded that these 275 substances do not meet any of the criteria set out in section 64 of the Act,

Notice therefore is hereby given that the Minister of the Environment and the Minister of Health (the ministers) propose to take no further action on four of the substances at this time.

And notice therefore is hereby given that the ministers propose to take no further action on the remaining 271 substances at this time under section 77 of the Act.

CATHERINE MCKENNA
Minister of the Environment

JANE PHILPOTT
Minister of Health

ANNEX I

Summary of the Screening Assessment

As part of the Chemicals Management Plan, the Government of Canada is assessing and managing, where appropriate, the potential health and ecological risks associated with certain polymers under the Canadian Environmental Protection Act, 1999 (CEPA). These polymers were identified as priorities for further action following the completion of the categorization in 2006. A section 71 notice for the second phase of the Domestic Substances List Inventory Update initiative was published in the Canada Gazette, Part I, in December 2012 to collect data on approximately 2 700 substances, including polymers. As a result of this data collection exercise, 336 polymers were identified as not being in commerce at quantities greater than 1 000 kg during the 2011 calendar year. A rapid screening approach was applied to these 336 polymers. It involved using conservative assumptions to identify polymers that warrant further evaluation of their potential to cause harm to either human health or the environment, and those that are expected to have a low likelihood of causing harmful ecological or human health effects.

The ecological component of the rapid screening approach of polymers consisted of four main steps to identify substances that warrant further evaluation of their potential to cause harm. The first step involved identifying the substances that have similar structural characteristics to polymeric substances that have been previously subject to risk management under the New Substances Notification Regulations (Chemicals and Polymers) [NSNR]. The second and third steps of the process involved identifying polymers that are likely to have water extractability greater than 2% and determining whether these polymers contain reactive functional groups, as described in items 1 and 5 of Schedule 7 of the NSNR, respectively. The final step involved applying different exposure scenarios using assumptions that are protective of the environment and drawing a comparison with a conservative acute ecotoxicity value for polymers.

The human health component of the rapid screening approach of polymers consisted of a process to determine whether each polymer warranted further assessment from a human health perspective. A key element of the characterization of potential risk for human health was a determination of the potential for exposure to the general population. Polymers reported to be in commerce in Canada at less than or equal to 1 000 kg during the 2011 calendar year are considered to warrant further assessment if there is evidence of direct exposure (e.g. exposure from products) of the general population in Canada. Polymers that posed a potential for direct exposure were also screened against a set of criteria in order to identify those likely to pose a low hazard to human health. If the potential for exposure to a polymer is not expected or the polymer is likely to pose a low hazard to human health, it is concluded that that polymer is unlikely to cause harm to human health at current levels of exposure.

Based on the information available, it is concluded that the 275 polymers listed in Annex II do not meet any of the criteria under section 64 of CEPA, since they are not entering the environment in a quantity or concentration or under conditions that have or may have an immediate or long-term harmful effect on the environment or its biological diversity, that constitute or may constitute a danger to the environment on which life depends, or that constitute or may constitute a danger in Canada to human life or health.

Conclusion

It is concluded that the 275 substances listed in Annex II do not meet any of the criteria set out in section 64 of CEPA.

The final screening assessment for these substances is available on the Government of Canada's Chemical Substances Web site (www.chemicalsubstances.gc.ca).

ANNEX II

Substances Identified as Not Meeting any of the Criteria Set Out in Section 64 of the Canadian Environmental Protection Act, 1999
CAS RN (see note a) or Confidential Accession Number (see note b) Substance name (see note c)
9003-37-6 Butanal, polymer with benzenamine
9003-50-3 Heptanal, polymer with benzenamine
9005-12-3 Poly[oxy(methylphenylsilylene)]
9008-63-3 Naphthalenesulfonic acid, sodium salt, polymer with formaldehyde
9016-83-5 Formaldehyde, polymer with methylphenol
9017-72-5 Naphthalenesulfonic acid, polymer with formaldehyde and 4,4′-sulfonylbis[phenol]
9022-96-2 1-Butanol, titanium(4+) salt, homopolymer
9060-53-1 2,5-Furandione, dihydro-3-(tetrapropenyl)-, polymer with 1-amino-2-propanol and 1,2-ethanediol
9086-40-2 Formaldehyde, polymer with (1,1,3,3-tetramethylbutyl)phenol
12624-35-0 9,12-Octadecadienoic acid (Z,Z)-, dimer, polymer with 1,2-ethanediamine
24937-74-4 Formaldehyde, polymer with benzenamine and phenol
24969-10-6 Oxirane, (chloromethyl)-, polymer with oxirane
25014-31-7 Benzene, (1-methylethenyl)-, homopolymer
25035-68-1 2-Propenoic acid, 2-methyl-, polymer with ethenylbenzene and ethyl 2-propenoate
25035-90-9 2-Butenedioic acid (Z)-, dibutyl ester, polymer with ethenyl acetate
25053-96-7 Formaldehyde, polymer with 2-methylphenol
25085-17-0 1,2-Ethanediamine, N-(2-aminoethyl)-, polymer with (chloromethyl)oxirane
25155-81-1 Formaldehyde, polymer with methylbenzene
25766-18-1 Bicyclo[3.1.1]hept-2-ene, 2,6,6-trimethyl-, homopolymer
25951-19-3 2-Propenoic acid, 2-methyl-, dodecyl ester, polymer with 5-ethenyl-2-methylpyridine and octadecyl 2-methyl-2-propenoate
26338-45-4 Aziridine, homopolymer, hydrochloride
26338-61-4 2-Furancarboxaldehyde, polymer with phenol
26591-12-8 Guanidine, cyano-, polymer with formaldehyde
26617-87-8 Oxirane, methyl-, polymer with oxirane, compd. with iodine
27553-53-3 Formaldehyde, polymer with 4-(1,1dimethylpropyl)phenol
27754-94-5 1,2-Ethanediamine, N,N′-bis(2-aminoethyl)-, polymer with (chloromethyl)oxirane
28472-87-9 Guanidine, cyano-, polymer with formaldehyde and 1,3,5-triazine-2,4,6-triamine
29086-67-7 Phenol, 4,4′-(1-methylethylidene)bis-, polymer with oxirane
30584-00-0 Formaldehyde, polymer with N-(3-aminopropyl)-1,3-propanediamine and 1,3,5-triazine-2,4,6-triamine
30705-14-7 Benzenesulfonamide, 2-methyl-, polymer with formaldehyde, 4-methylbenzenesulfonamide and 1,3,5-triazine-2,4,6-triamine
32311-19-6 Urea, polymer with formaldehyde and 1,3,5,7-tetraazatricyclo[3.3.1.13,7]decane
32761-96-9 Benzenediazonium, 2-methoxy-4-(phenylamino)-, salt with 2,4,6-trimethylbenzenesulfonic acid (1:1) polymer with 1,1′-oxybis[4-(methoxymethyl)benzene]
32844-27-2 Carbonic dichloride, polymer with 4,4′-(1-methylethylidene)bis[2,6-dibromophenol] and 4,4′-(1-methylethylidene)bis[phenol]
34323-39-2 Oxirane, (chloromethyl)-, polymer with ammonium hydroxide ((NH4)(OH))
34802-28-3 Formaldehyde, polymer with benzenamine, methyloxirane, oxirane and phenol
35297-54-2 Formaldehyde, polymer with ammonia and phenol
37189-83-6 9,12-Octadecadienoic acid (Z,Z)-, dimer, polymer with N-(2-aminoethyl)-1,2-ethanediamine
37238-34-9 Formaldehyde, polymer with nonylphenol and phenol
37281-91-7 Lignin, polymer with formaldehyde and phenol
37337-65-8 Formaldehyde, polymer with phenol and 1,3,5,7-tetraazatricyclo[3.3.1.13,7]decane
37604-36-7 Formaldehyde, polymer with phenol and 4-(1,1,3,3-tetramethylbutyl)phenol
37625-74-4 Urea, polymer with N-(2-aminoethyl)-1,2-ethanediamine, N,N′-bis(2-aminoethyl)-1,2-ethanediamine and formaldehyde
37625-93-7 2-Propenoic acid, polymer with (chloromethyl)oxirane and 4,4′-(1-methylethylidene)bis[phenol]
40364-42-9 Phenol, 4,4′-(1-methylethylidene)bis-, polymer with (chloromethyl)oxirane and 4,4′-methylenebis[benzenamine]
52108-93-7 (see note d) Lignin, ammonium salt
53740-05-9 Dextrin, polymer with formaldehyde
61472-52-4 Urea, polymer with N-(2-aminoethyl)-1,2-ethanediamine and formaldehyde
61827-83-6 Lignosulfonic acid, copper salt
62073-57-8 Urea, N,N′-bis(hydroxymethyl)-, polymer with formaldehyde and (hydroxymethyl)urea
63494-85-9 Formaldehyde, polymer with 4-methyl-2-nonylphenol and 4-methylphenol
63512-71-0 Formaldehyde, polymer with ammonia and chloroethane
63784-89-4 Benzenesulfonic acid, 4-amino-, monosodium salt, polymer with formaldehyde and methylphenol
63951-50-8 Naphthalenesulfonic acid, sodium salt, polymer with formaldehyde and 4,4′-sulfonylbis[phenol]
65733-73-5 Formaldehyde, polymer with 4,4′-(1-methylethylidene)bis[phenol] and 4-(1,1-dimethylpropyl)phenol
65733-79-1 Phenol, polymer with 1-methyl-4-(1-methylethenyl)cyclohexene and 2,6,6-trimethylbicyclo[3.1.1]hept-2-ene
65733-82-6 Formaldehyde, polymer with 4-(1,1-dimethylethyl)phenol, 4,4′-(1-methylethylidene)bis[phenol] and 4-(1,1,3,3-tetramethylbutyl)phenol
65997-11-7 Rosin, fumarated, polymer with pentaerythritol
67763-03-5 Silsesquioxanes, Me Ph
67784-93-4 Formaldehyde, polymer with 2-methylphenol and phenol, sulfonated, sodium salt
67784-97-8 Naphthalenesulfonic acids, polymers with formaldehyde and sulfonated phenol, sodium salts
67786-28-1 2-Naphthalenesulfonic acid, 6-hydroxy-, polymer with formaldehyde, 3-methylphenol and 4-methylphenol, sodium salt
67816-01-7 Propanoic acid, 3-hydroxy-2-(hydroxymethyl)-2-methyl-, polymer with 1,4-cyclohexanedimethanol, 1,3-diisocyanatomethylbenzene, hydrazine and α-hydro-ω-hydroxypoly(oxy-1,4-butanediyl)
67846-45-1 1,3-Propanediamine, N-9-octadecenyl-, (Z)-, polymer with (chloromethyl)oxirane and α-hydro-ω-hydroxypoly(oxy-1,2-ethanediyl)
67905-95-7 Formaldehyde, polymer with 4-(1,1-dimethylethyl)phenol and 4-nonylphenol
67924-33-8 Ethanol, 2,2′,2″-nitrilotris-, homopolymer, hydrochloride
67953-56-4 1,6-Hexanediamine, N-(6-aminohexyl)-, polymer with (chloromethyl)oxirane
67953-82-6 Phenol, 4-dodecyl-, polymer with 1,2-ethanediamine and formaldehyde, compd. with (dibutylamino)methanol
67970-32-5 Formaldehyde, polymer with 4-(1,1-dimethylethyl)phenol and methylphenol
68003-26-9 Formaldehyde, polymer with ammonia and 2-methylphenol
68015-68-9 Poly(oxy-1,2-ethanediyl), α-hydro-ω-hydroxy-, ether with 1-[[2-[[2-[bis(2-hydroxyethyl)amino]ethyl](2hydroxyethyl)amino]ethyl](2-hydroxyethyl)amino]-3-(9-octadecenyloxy)-2-propanol (4:1), (Z)-
68036-98-6 Imidazo[4,5-d]imidazole-2,5(1H,3H)-dione, tetrahydro-, polymer with formaldehyde, butylated
68037-87-6 Siloxanes and Silicones, Me vinyl
68072-45-7 1,4-Pentadien-3-one, 1,5-bis[4(oxiranylmethoxy)phenyl]-, polymer with 4,4′-(1-methylethylidene)bis[2,6-dibromophenol] and 4,4′-(1-methylethylidene)bis[phenol]
68082-23-5 Cyclosiloxanes, Me vinyl
68082-91-7 Rosin, fumarated, polymer with formaldehyde, potassium sodium salt
68082-95-1 Rosin, maleated, polymer with bisphenol A, formaldehyde, glycerol and pentaerythritol
68083-27-2 Soybean oil, polymer with ethylenediamine, linoleic acid dimer, pentaerythritol, phthalic anhydride and tall oil
68123-23-9 Nonanedioic acid, polymer with 1,2-ethanediamine, 1,6-hexanediamine and (Z,Z)-9,12-octadecadienoic acid dimer
68130-98-3 Aziridine, homopolymer, ethoxylated, phosphonomethylated
68134-00-9 Decanedioic acid, polymer with 1,2-ethanediamine, 1,6-hexanediamine and (Z,Z)-9,12-octadecadienoic acid dimer
68140-39-6 Formaldehyde, polymer with (chloromethyl)oxirane, 4,4′-(1-methylethylidene)bis[phenol], methyloxirane, methyloxirane polymer with oxirane ether with 1,2,3-propanetriol (3:1), nonylphenol and oxirane
68152-47-6 Rosin, fumarated, polymer with bisphenol A, formaldehyde and pentaerythritol
68152-60-3 Rosin, maleated, polymer with bisphenol A, formaldehyde and glycerol
68152-67-0 Rosin, maleated, polymer with tripentaerythritol
68152-68-1 Rosin, polymer with bisphenol A and formaldehyde
68154-31-4 Fatty acids, C14-18, ethoxylated propoxylated
68155-33-9 Amines, C14-18-alkyl, ethoxylated
68155-40-8 Amines, C16-18 and C18-unsatd. alkyl, ethoxylated
68188-28-3 Tall-oil rosin, maleated, polymer with pentaerythritol
68188-63-6 Rosin, maleated, polymer with bisphenol A and formaldehyde
68188-92-1 Amines, tallow alkyl, propoxylated
68201-58-1 Rosin, fumarated, polymer with formaldehyde
68213-26-3 Amines, tallow alkyl, ethoxylated propoxylated
68213-35-4 Fatty acids, C18-unsatd., dimers, polymers with ethylenediamine, 4-hydroxy-γ-(4-hydroxyphenyl)-γ-methylbenzenebutanoic acid and oleic acid
68240-07-3 Phenol, polymer with 6,6-dimethyl-2-methylenebicyclo[3.1.1]heptane and 2,6,6-trimethylbicyclo[3.1.1]hept-2-ene
68240-08-4 Phenol, polymer with 3-methylene-6-(1methylethyl)cyclohexene, 1-methyl-4-(1methylethenyl)cyclohexene, 1-methyl-4-(1-methylethyl)-1,3-cyclohexadiene, 1-methyl-4-(1-methylethyl)1,4-cyclohexadiene, 2-methyl-5-(1-methylethyl)1,3-cyclohexadiene, 1-methyl-4(1-methylethylidene)cyclohexene and 2,6,6-trimethylbicyclo[3.1.1]hept-2-ene
68310-21-4 Poly(oxy-1,2-ethanediyl), α-hydro-ω-hydroxy-, ether with α-[[(2-hydroxyethyl)[2-[[2[(2-hydroxyethyl)octadecylamino]ethyl](2-hydroxy-2-phenylethyl)amino]ethyl]amino]methyl]benzenemethanol (2:1)
68332-89-8 Aziridine, homopolymer, propoxylated, benzyl chloride-quaternized
68333-40-4 Tung oil, polymer with boron trifluoride-phenol complex, formaldehyde, phenol, β-pinene and turpentine oil
68333-98-2 (see note d) Coconut oil, ester with polyethylene glycol mono(nonylphenyl) ether
68379-09-9 Benzenesulfonamide, ar-methyl-, polymer with formaldehyde and tetrahydroimidazo[4,5-d]imidazole-2,5(1H,3H)-dione
68390-20-5 Fatty acids, sunflower-oil, polymers with adipic acid, caprolactam, diethylenetriamine and triethylenetetramine
68400-14-6 Guanidine, cyano-, polymer with 1,2-ethanediamine sulfate (1:1) and formaldehyde
68410-22-0 (see note d) Fatty acids, C18-unsatd., dimers, reaction products with diethylenetriamine
68412-14-6 Octadecanoic acid, reaction products with 2-[(2-aminoethyl)amino]ethanol and urea
68440-73-3 Siloxanes and Silicones, di-Me, Me Ph, hydroxy-terminated
68441-69-0 1,2-Ethanediamine, polymer with 1,3-diisocyanatomethylbenzene, reaction products with oleylamine
68479-80-1 Phenol, polymer with 1,2-cyclohexanediamine, formaldehyde and 1,6-hexanediamine
68511-76-2 2,5-Furandione, polymer with formaldehyde and 1,3,5-triazine-2,4,6-triamine, butylated isopropylated, reaction products with triethylamine
68512-34-5 (see note d) Lignosulfonic acid, sodium salt, sulfomethylated
68513-37-1 Fatty acids, tall-oil, polymers with diethylenetriamine and linoleic acid dimers
68513-38-2 Fatty acids, tall-oil, polymers with diethylenetriamine, linoleic acid dimers and triethylenetetramine
68516-42-7 2-Propenoic acid, 2-methyl-, 2-[(1,1dimethylethyl)amino]ethyl ester, polymer with methyl 2-methyl-2-propenoate and 2-methylpropyl 2-methyl-2-propenoate
68516-43-8 2-Propenoic acid, 2-methyl-, polymer with 2-methylaziridine, methyl 2-methyl-2-propenoate and 2-methylpropyl 2-methyl-2-propenoate
68516-87-0 Benzenesulfonic acid, 2,4-dimethyl-, polymer with formaldehyde and 4,4′-sulfonylbis[phenol], ammonium sodium salt
68527-87-7 Formaldehyde, polymer with 2-ethoxyethanol and phenol
68540-48-7 9,12-Octadecadienoic acid (Z,Z)-, dimer, compd. with N,N′-bis(2-aminoethyl)-1,2-ethanediamine
68540-71-6 Benzoic acid, 2-hydroxy-, polymer with formaldehyde, 2-methylphenol and nonylphenol
68541-21-9 9,12-Octadecadienoic acid (Z,Z)-, polymer with (chloromethyl)oxirane and 4,4′(1-methylethylidene)bis[phenol]
68541-77-5 Decanedioic acid, polymer with 2-aminoethanol, 1,2-ethanediamine and (Z,Z)-9,12-octadecadienoic acid dimer
68552-99-8 Fatty acids, vegetable-oil, polymers with phthalic anhydride and rosin
68553-78-6 Oils, oiticica, polymers with boron trifluoride-phenol complex, formaldehyde, phenol, β-pinene and turpentine oil
68554-18-7 Rosin, fumarated, polymer with glycerol, ammonium salt
68604-06-8 Castor oil, hydrogenated, polymer with ethylenediamine, 12-hydroxyoctadecanoic acid and sebacic acid
68605-92-5 Fatty acids, tall-oil, reaction products with polyethylenepolyamines, compds. with polyethylene glycol decyl ether phosphate
68606-78-0 Naphthenic acids, esters with polytriethanolamine
68609-24-5 Formaldehyde, polymer with benzenamine, propoxylated
68610-07-1 Formaldehyde, polymers with isobutylenated phenol
68610-55-9 Phenol, 4,4′-(1-methylethylidene)bis-, polymer with (chloromethyl)oxirane and phenyloxirane, reaction products with 4,4′-methylenebis[benzenamine]
68610-75-3 2-Propenoic acid, 2-methyl-, methyl ester, polymer with 2-mercaptoethanol, reaction products with ammonia and N,N′,2-tris(6-isocyanatohexyl)imidodicarbonic diamide
68650-48-6 Fatty acids, C18-unsatd., dimers, polymers with C18-unsatd. alkyl amine dimers and ethylenediamine
68890-97-1 Aziridine, homopolymer, compd. with (chloromethyl)benzene
68891-01-0 Benzenesulfonamide, ar-methyl-, polymer with formaldehyde and 1,3,5-triazine-2,4,6-triamine, butylated
68910-67-8 Rosin, fumarated maleated, polymer with formaldehyde, potassium sodium salt
68915-81-1 Linseed oil, polymer with bisphenol A, bisphenol A diglycidyl ether, diethylenetriamine, formaldehyde, glycidyl Ph ether and pentaethylenehexamine
68920-24-1 Fatty acids, dehydrated castor-oil, polymers with bisphenol A, epichlorohydrin, fumaric acid and rosin
68920-41-2 Fatty acids, tall-oil, reaction products with polyethylenepolyamines, compds. with polyethylene glycol monooctyl ether phosphate
68937-31-5 4,6,10-Dodecatrien-3-one, 7,11-dimethyl-, cyclized, by-products from, fractionation residues
68951-99-5 Siloxanes and Silicones, di-Me, Me vinyl, mono(vinyl group)-terminated
68952-00-1 Siloxanes and Silicones, di-Me, mono(vinyl group)-terminated
68953-74-2 Aziridine, homopolymer, ethoxylated, phosphonomethylated, sodium salt
68956-65-0 Naphthenic acids, polymers with ethylenimine, compds. with linoleic acid dimer
68988-41-0 Phenol, 4,4′-(1-methylethylidene)bis-, polymer with (chloromethyl)oxirane, reaction products with diethanolamine and polyethylene glycol monooleate
68988-81-8 Hexanedioic acid, polymer with bis(2-chloroethyl) (1-hydroxyethyl)phosphonate, 2-chloroethyl hydrogen (2-chloroethyl)phosphonate, 2-chloroethyl hydrogen (1-hydroxyethyl)phosphonate, (E)-2,3-dibromo-2-butene-1,4-diol, 1,3-diisocyanatomethylbenzene and 2,2′-oxybis[ethanol], reaction products with diethanolamine, hydrochlorides
68988-82-9 Hexanedioic acid, polymer with bis(2-chloroethyl) (1-hydroxyethyl)phosphonate, 2-chloroethyl hydrogen (2-chloroethyl)phosphonate, 2-chloroethyl hydrogen (1-hydroxyethyl)phosphonate, (E)-2,3-dibromo-2-butene-1,4-diol, 1,3-diisocyanatomethylbenzene and 1,2-propanediol, reaction products with diethanolamine, hydrochlorides
68989-80-0 Fatty acids, linseed-oil, polymers with glycerol, maleic anhydride, phthalic anhydride, rosin and tung oil
69011-21-8 Benzene, diethenyl-, polymer with ethenylbenzene and ethenylethylbenzene, sulfonated, ammonium salts
69178-40-1 Formaldehyde, polymer with benzenamine and 2-ethylbenzenamine
69898-35-7 Urea, polymer with formaldehyde and 1,3,5,7-tetraazatricyclo[3.3.1.13,7]decane, butylated
69898-36-8 Urea, polymer with formaldehyde and 1,3,5,7-tetraazatricyclo[3.3.1.13,7]decane, butylated ethylated
69929-35-7 Decanedioic acid, polymer with 1,2-ethanediamine, (Z,Z)-9,12-octadecadienoic acid dimer and 4,4′-(1,3-propanediyl)bis[piperidine]
69929-44-8 9,12-Octadecadienoic acid (Z,Z)-, dimer, polymer with 5-amino-1,3,3-trimethylcyclohexanemethanamine and 1,2-ethanediamine, acetate
70528-79-9 Sulfite liquors and Cooking liquors, spent, polymer with formaldehyde
70693-20-8 Cyanamide, reaction products with carbon dioxide, ethylene oxide and 1-octadecanamine
70750-07-1 Formaldehyde, polymer with N-(2-aminoethyl)-1,2-ethanediamine, benzylated
70851-21-7 Siloxanes and Silicones, di-Me, (C3-33-alkyloxy)-terminated
71042-85-8 2-Propenoic acid, 2-methyl-, telomer with 2-[(1,1-dimethylethyl)amino]ethyl 2-methyl-2-propenoate, 1-dodecanethiol, methyl 2-methyl-2-propenoate and exo-1,7,7-trimethylbicyclo[2.2.1]hept-2-yl 2-methyl-2-propenoate
71077-22-0 Benzoic acid, 2-hydroxy-, polymer with formaldehyde, 4-nonylphenol and zinc oxide (ZnO)
71412-29-8 2-Propenoic acid, 2-methyl-, 2-hydroxyethyl ester, telomer with tert-dodecanethiol, ethenylbenzene, isodecyl 2-methyl-2-propenoate and 2-propenoic acid, compd. with 2-(dimethylamino)ethanol
72121-75-6 Formaldehyde, polymer with 2,2′-iminobis[ethanol], 4,4′-(1-methylethylidene)bis[phenol], nonylphenol and 1,3,5-triazine-2,4,6-triamine
72207-55-7 Benzenamine, ethylenated, distn. residues
72361-56-9 Phenol, 4,4′-(1-methylethylidene)bis-, polymer with 5-amino-1,3,3-trimethylcyclohexanemethanamine, (butoxymethyl)oxirane and (chloromethyl)oxirane
72828-15-0 Benzene, diethenyl-, polymer with ethenylbenzene, sulfonated, ammonium salts
72968-37-7 Amines, C12-18-alkyl, ethoxylated
73049-34-0 Alcohols, C16-20, ethoxylated propoxylated
73297-33-3 Poly(oxy-1,2-ethanediyl), α-[tris[1(methylphenyl)ethyl]phenyl]-ω-hydroxy-
75790-74-8 1,2,3-Propanetriol, polymer with 1,3-diisocyanatomethylbenzene, hydrazine, methyloxirane and oxirane
76649-36-0 Formic acid, compd. with N-(2-aminoethyl)-1,2-ethanediamine polymer with formaldehyde and urea
76649-37-1 Hexanedioic acid, polymer with N-(2-aminoethyl)-1,2-ethanediamine, ammonia, (chloromethyl)oxirane, formaldehyde and formic acid, formate hydrochloride sulfate
76649-45-1 Hexanedioic acid, polymer with N-(2-aminoethyl)-1,2-ethanediamine, (chloromethyl)oxirane, formaldehyde and formic acid
76649-46-2 Hexanedioic acid, polymer with N-(2-aminoethyl)-1,2-ethanediamine, (chloromethyl)oxirane, formaldehyde and formic acid, formate hydrochloride sulfate
76822-95-2 Imides, cyclic, from C15-20 α-alkene-maleic anhydride copolymer and (Z)-N-9-octadecenyl-1,3-propanediamine
79770-99-3 Fatty acids, C18-unsatd., dimers, distn. lights, reaction products with α,α′-(1-methyl-1,3propanediyl)bis[ω-hydroxypoly(oxy-1,2-ethanediyl)]
82640-14-0 Naphthalenesulfonic acids, polymers with formaldehyde, sulfonated 1,1′-oxybis[methylbenzene] and sulfonylbis[phenol], ammonium sodium salts
89394-61-6 Formaldehyde, polymer with N-(2-aminoethyl)-N′-[2-[(2-aminoethyl)amino]ethyl]-1,2-ethanediamine and benzenamine
95012-79-6 Tetraglycerol, monododecyl ether
95649-04-0 Naphthalenesulfonic acids, polymers with formaldehyde, sulfonated 1,1′-biphenyl and sulfonylbis[phenol], ammonium sodium salts
95649-08-4 Formaldehyde, polymers with sulfonated terphenyl and sulfonylbis[phenol], ammonium sodium salts
96591-18-3 Fatty acids, tall-oil, reaction products with 2-amino-2-(hydroxymethyl)-1,3-propanediol and formaldehyde, polymers with acrylonitrile, Et acrylate and Me methacrylate
96591-23-0 Formaldehyde, polymers with sulfonated 1,1′-biphenyl, sulfonated terphenyl and sulfonylbis[phenol], ammonium sodium salts
97969-64-7 Propanoic acid, 3-hydroxy-2-(hydroxymethyl)-2-methyl-, polymer with 1-aziridineethanol, formaldehyde, 1,6-hexanediol and 1,3,5-triazine-2,4,6-triamine
98654-27-4 Fatty acids, dehydrated castor-oil, polymers with dehydrated castor oil, 2-(dimethylamino)ethanol, isononanoic acid, isophthalic acid, linseed oil, maleic anhydride and pentaerythritol
100588-10-1 2-Propenoic acid, polymer with 2,2′-[1,2ethanediylbis(oxymethylene)]bis[oxirane] and sodium 2-propenoate
102082-95-1 2-Propenoic acid, ammonium salt, polymer with 2-propenamide and 2-propenenitrile
102561-59-1 Hexanedioic acid, polymer with N-(2-aminoethyl)-1,3-propanediamine and N,N″-1,2-ethanediylbis[1,3-propanediamine]
102984-13-4 2-Propenoic acid, sodium salt, polymer with 2,2′-[1,2-ethanediylbis(oxymethylene)]bis[oxirane]
103458-43-1 2-Propenoic acid, polymer with 2-(diethylamino)ethyl 2-propenoate and 2-propenamide, sulfate
104376-66-1 Formaldehyde, polymers with branched nonylphenol, ethylene oxide and hexamethylenediamine
106214-62-4 Fatty acids, soya, polymers with adipic acid, 1,6-hexanediol, 3-hydroxy-2-(hydroxymethyl)-2-methylpropanoic acid, 5-isocyanato-1-(isocyanatomethyl)-1,3,3-trimethylcyclohexane, isophthalic acid and trimethylolpropane, compds. with triethylamine
106214-63-5 Fatty acids, soya, polymers with benzoic acid, 3-hydroxy-2-(hydroxymethyl)-2-methylpropanoic acid, 5-isocyanato-1-(isocyanatomethyl)-1,3,3-trimethylcyclohexane, isophthalic acid, pentaerythritol and phthalic anhydride, compds. with triethylamine
108563-09-3 Amines, tallow alkyl, ethoxylated, 4-dodecylbenzenesulfonates (salts)
110392-46-6 Formaldehyde, reaction products with 1,4-benzenediol and m-phenylenediamine, sulfurized
110720-55-3 Oxirane, methyl-, polymer with oxirane, ether with [[3-[(2hydroxymethylethyl)amino]propyl]imino]bis[propanol] (3:1), N-tallow alkyl derivs., sulfates (esters), ammonium salts
112484-41-0 Formaldehyde, polymer with 4-(1,1,3,3tetramethylbutyl)phenol, hydrobromic acid-terminated
115559-71-2 Sulfurous acid, monosodium salt, reaction products with m-cresol-formaldehyde-nonylphenol polymer
115559-72-3 Sulfurous acid, monosodium salt, reaction products with m-cresol-formaldehyde polymer
116265-69-1 Formaldehyde, reaction products with hexamethylenediamine and oxidized ethylene-propene polymer
117985-54-3 Benzenesulfonic acid, hydroxy-, monosodium salt, polymer with benzenamine, formaldehyde, 1,3,5-triazine-2,4,6-triamine and urea, bisulfited
118460-96-1 Formaldehyde, polymer with methylphenol, nonylphenol and phenol, bisulfited
118685-17-9 Benzenesulfonic acid, 4-amino-, polymer with formaldehyde, 2-methylphenol and phenol, bisulfited
119147-80-7 Octadecanoic acid, 12-hydroxy-, homopolymer, 2-hydroxy-3-[(2-methyl-1-oxo-2-propenyl)oxy]propyl ester, polymer with methyl 2-methyl-2-propenoate and oxiranylmethyl 2-methyl-2-propenoate, 2-methyl-2-propenoate 4-nitrobenzoate
121028-89-5 2-Propenoic acid, 2-methyl-, telomer with butyl 2-methyl-2-propenoate, 1-dodecanethiol, 2-mercaptoethanol, methyl 2-methyl-2-propenoate and 2-(3-oxazolidinyl)ethyl 2-methyl-2-propenoate
121053-40-5 Amines, N-coco alkyltrimethylenedi-, compds. with acrylic acid-N-(butoxymethyl)-2-propenamide-Et acrylate-styrene polymer and 2-(dimethylamino)ethanol
121053-44-9 Pentanedioic acid, dimethyl ester, polymer with N-(2-aminoethyl)-1,2-ethanediamine, ammonia and (chloromethyl)oxirane
121053-47-2 Propanoic acid, 2-hydroxy-, compd. with (chloromethyl)oxirane polymer with 2-(methylamino)ethanol, 4,4′-(1methylethylidene)bis[phenol] and α,α′-[(1methylethylidene)di-4,1phenylene]bis[ω-hydroxypoly(oxy-1,2-ethanediyl)]
121372-53-0 2-Propenoic acid, 2-methyl-, methyl ester, telomer with butyl 2-propenoate, tert-dodecanethiol, ethenylbenzene, 2-(methylamino)ethanol and oxiranylmethyl 2-methyl-2-propenoate, (±)-2-hydroxypropanoate (salt) (S)-2-hydroxypropanoate (salt)
121375-94-8 Urea, polymer with benzenamine, formaldehyde and 1,3,5-triazine-2,4,6-triamine, bisulfited
121617-09-2 Alcohols, C16-18, propoxylated
121617-10-5 Rosin, polymd., polymer with maleic anhydride, phthalic anhydride, tall oil, tetrahydroabietyl alc. and trimethylolpropane
122966-99-8 Phenol, 2,4,6-tris(1-methylpropyl)-, reaction products with 2,2′-[(1-methylethylidene)bis(4,1-phenyleneoxymethylene)]bis[oxirane], ethoxylated
123774-67-4 Formaldehyde, polymer with ammonium hydroxide ((NH4)(OH)), 4-(1,1-dimethylethyl)phenol and phenol
124578-08-1 1,3-Butadiene, 2-chloro-, homopolymer, reaction products with zinc oxide
125249-27-6 Formaldehyde, polymer with methanol and nonylphenol
125302-07-0 2-Propenamide, polymer with formaldehyde and morpholine
125302-08-1 Phenol, 4,4′-(1-methylethylidene)bis-, polymer with 2,2′-iminobis[ethanol], 2,2′-[(1-methylethylidene)bis(4,1-phenyleneoxymethylene)]bis[oxirane] and 4-nonylphenol
125328-35-0 Amides, from hydrogenated tallow and tetraethylenepentamine, polymers with epichlorohydrin and polyethylene glycol, acetates (salts)
125328-72-5 2-Propenoic acid, 2-methyl-, methyl ester, telomer with butyl 2-propenoate, tert-dodecanediol, ethenylbenzene, 2-(methylamino)ethanol, oxiranylmethyl 2-methyl-2-propenoate and 1,2-propanediol
125329-08-0 9-Octadecenoic acid (Z)-, polymer with copper(2+) sulfate (1:1), 2,5-furandione and oxybis[propanol]
125351-98-6 Aziridine, homopolymer, reaction products with epichlorohydrin and polyethylene glycol, acetates
125352-08-1 Amines, N-C12-22-alkyltrimethylenedi-, ethoxylated
125352-10-5 Sulfuric acid copper(2+) salt (1:1), polymer with 2,5-furandione and oxybis[propanol]
125378-97-4 2-Propenoic acid, butyl ester, polymer with ethenylbenzene, methyl 2-methyl-2-propenoate, oxiranylmethyl 2-methyl-2-propenoate, 1,2-propanediol mono(2-methyl-2-propenoate) and 2,2′-thiobis[ethanol]
125826-31-5 1,2-Benzenedicarboxylic acid, di-2-propenyl ester, polymer with (Z)-butyl hydrogen 2-butenedioate, butyl 2-methyl-2-propenoate, ethenylbenzene, 2-ethylhexyl 2-propenoate, 2-hydroxyethyl 2-methyl-2-propenoate, 12-hydroxyoctadecanoic acid homopolymer 2-hydroxy-3-[(2-methyl-1-oxo-2-propenyl)oxy]propyl ester, methyl 2-methyl-2-propenoate, 2-methyl-2-propenoic acid and oxiranylmethyl 2-methyl-2-propenoate, 4-nitrobenzoate
125826-39-3 Propanoic acid, 3-hydroxy-2-(hydroxymethyl)-2-methyl-, polymer with 1,4-cyclohexanedimethanol, 1,3-diisocyanatomethylbenzene, hydrazine and α-hydro-ω-hydroxypoly(oxy-1,4-butanediyl), compd. with N,N-diethylethanamine
128801-08-1 Formaldehyde, polymer with 4,4′-(1methylethylidene)bis[phenol], 2,2′-[(1methylethylidene)bis(4,1phenyleneoxymethylene)bis[oxirane] and phenol
128971-25-5 Fatty acids, polymers with isophthalic acid, linoleic acid dimer and triethylenetetramine
129126-83-6 Linseed oil, polymer with benzoic acid, formaldehyde, pentaerythritol, phenol, phthalic anhydride, rosin, TDI, 3a,4,7,7a-tetrahydro-1,3-isobenzofurandione and trimethylolpropane
129126-87-0 Linseed oil, polymer with benzoic acid, formaldehyde, pentaerythritol, phenol, phthalic anhydride, rosin, TDI, 3a,4,7,7a-tetrahydro-1,3-isobenzofurandione and trimethylolpropane, compds. with 2-(dimethylamino)ethanol
129420-90-2 Phenol, 4,4′-(1-methylethylidene)bis-, polymer with 2,2′-iminobis[ethanol] and 2,2′-[(1methylethylidene)bis(4,1phenyleneoxymethylene)]bis[oxirane]
129783-27-3 Guanidine, cyano-, polymer with formaldehyde and 1,3,5-triazine-2,4,6-triamine, sulfonated, sodium salts
129783-43-3 Phenol, 4,4′-(1-methylethylidene)bis-, polymer with 2,2′-iminobis[ethanol] and 2,2′-[(1methylethylidene)bis(4,1phenyleneoxymethylene)]bis[oxirane], reaction products with polyethylene glycol monostearate
129783-50-2 Benzenesulfonamide, 4-amino-, polymer with (chloromethyl)oxirane, 4,4′-(1-methylethylidene)bis[2,6-dibromophenol] and 2,2′-[(1-methylethylidene)bis(4,1-phenyleneoxymethylene)]bis[oxirane]
129870-85-5 Hexanedioic acid, polymer with 1,3-isobenzofurandione, 5-isocyanato-1-(isocyanatomethyl)-1,3,3-trimethylcyclohexane and oxybis[propanol], 2-hydroxyethyl acrylate-blocked
144030-98-8 Benzenesulfonic acid, 4-hydroxy-, polymer with formaldehyde and urea, reaction products with aniline, 1,3-bis(hydroxymethyl)urea, 4,5-dihydroxy1,3-bis(hydroxymethyl)-2-imidazolidinone, disodium disulfite, formaldehyde, tetrahydro-3,5-bis(hydroxymethyl)-1
144031-00-5 Propanoic acid, 2-hydroxy-, compds. with bisphenol A-epichlorohydrin-polyethylene glycol ether with bisphenol A (2:1) polymer-2-(methylamino)ethanol reaction products
144238-33-5 2-Propenoic acid, 2-methyl-, reaction products with bisphenol A-bisphenol A diglycidyl ether polymer benzoate and styrene
147170-42-1 2-Propenoic acid, telomer with 1-dodecanethiol, S-oxides, ammonium salts
150226-40-7 Formaldehyde, polymer with 4-(1,1-dimethylethyl)phenol, 4,4′-(1-methylethylidene)bis[phenol] and 4-methylphenol, magnesium oxide complex
150226-41-8 Formaldehyde, polymer with 4-(1,1-dimethylethyl)phenol and 4,4′-(1-methylethylidene)bis[phenol], magnesium oxide complex
154862-02-9 Rosin, polymd., polymer with maleic anhydride, phthalic anhydride, tall oil, tetrahydroabietyl alc. and trimethylolethane
155240-18-9 Benzenesulfonic acid, dodecyl-, reaction products with succinic anhydride monopolyisobutylene derivs., tetraethylenepentamine and zinc oxide
160611-46-1 2,5-Furandione, telomer with ethenylbenzene and (1-methylethyl)benzene, C8-rich C7-9-isoalkyl esters
165307-61-9 1,3-Isobenzofurandione, polymer with 2,2-bis(hydroxymethyl)-1,3-propanediol and 1,2,3-propanetriol, benzoate (9Z,12Z)-9,12-octadecadienoate
176227-30-8 Formaldehyde, polymer with 4-(1,1-dimethylethyl)phenol and oxirane, esters with tall-oil fatty acids
10008-0 (see note b) Phenol, 4,4′-(1-methylethylidene)bis-, polymer with 2,2′-[(1-methylethylidene)bis(4,1-phenyleneoxymethylene)]bis[oxirane] and diethanolamine and poly(oxyalkylenediyl), α-(1-oxo-9-octadecenyl)-ω-hydroxy-, (Z)-
10009-1 (see note b) Phenol, 4,4′-(1-methylethylidene)bis-, polymer with 2,2′-[(1-methylethylidene)bis(4,1-phenyleneoxymethylene)]bis[oxirane] and bis(2-substituted ethyl) amine
10011-3 (see note b) Cyanoguanidine polymer with diammonium sulfate and an alkyl aldehyde
10017-0 (see note b) Amido amine composed of 1,3-propanediamine, N-(3-aminoalkyl)-N-methyl and fatty acids, C18-unsaturated dimers
10697-5 (see note b) Metal alkenylsuccinate
10709-8 (see note b) Piperazine, 1,2-alkyldiamine, formaldehyde and (chloromethyl)oxirane, polymer
11048-5 (see note b) Fatty acids, tall-oil, reaction products with polyethylene glycol, and dicarboxylic acid, salt with reaction products of fatty acids, tall-oil and polyalkylenepolyamine
11054-2 (see note b) Nonyl phenol, ethoxylated, monoester with dicarboxylic acid, neutralized with reaction products of tall-oil fatty acids and polyalkylenepolyamine
11065-4 (see note b) Fatty acids, tall oil, reaction product with polyalkyenepolyamine and phosphoric acid
11108-2 (see note b) Phosphoric acid, polysubstituted amino resin, amino substituted borate
11111-5 (see note b) Amino amide composed of 1,4-piperazinedialkylamine and fatty acids, C18-unsatd. dimers
11114-8 (see note b) Phenol, 4,4′-(1-methylethylidene)bis-, polymer with 2′-[(1-methylethylidene)bis(4,1phenyleneoxymethylene)]bisoxirane] and diethanolamine and poly(oxyalkylenediyl), α.-oxooctadecyl)-ω-hydrox-
11118-3 (see note b) Phenol, 4,4′-(1-methylethylidene)bis-, polymer with chloromethyl)oxirane, 1,3,5-triazine-2,4,6-triamine polymer with formaldehyde, and substituted benzoic acid, 1-propanol, 2-(dimethylamino)-2-methyl-, salt
11126-2 (see note b) Substituted bis disubstituted heteropolycycle, polymer with (chloromethyl)oxirane, dihydro-2,5-furandione and 4,4′-(1-methylethylidene)bis[phenol], alkanoate, 2-propenoate, metal salt
11135-2 (see note b) Tall oil rosin, polymer with alkanoic acid, disubstituted heteropolycyclic acid and 1,3-propanediol, 2-ethyl-2-(hydroxymethyl)-
11147-5 (see note b) Polymer of aromatic acids, tall oil fatty acid, polyols, N,N-dimethylethanolamine, methanol, melamine and formaldehyde
11154-3 (see note b) Polymer of linseed oil, pentaerythritol, isophthalic acid, monobasic acid, rosin, and maleic anhydride
11176-7 (see note b) Fatty acids, C18-unsaturated, dimers, polymers with tall-oil fatty acids and tetraethylenepentamine, reaction products with bisphenol A-epichlorhydrin condensate and polyalkylenepolyamines
11201-5 (see note b) Polymer of linseed and chinawood oils and synthetic rosin, pentaerythritol and solid resin
11431-1 (see note b) Poly(allyl methacrylate/butyl acrylate/2-substituted ethyl acrylate/methacrylic acid/methyl methacrylate) 2-amino-2-methyl-1-propanol salt
11436-6 (see note b) Reaction product of alkenylsarcosine, polyoxypropylenediamine and zinc stearate
11459-2 (see note b) Naphtha (petroleum), light steam cracked, debenzenised, polymer with alkylphenol and formaldehyde
11461-4 (see note b) Rosin, maleated, polymer with a carbonyl compound and pentaerythritol, calcium, magnesium and zinc salts
11470-4 (see note b) Rosin, polymer with p-tert-butylphenol, formaldehyde, glycerol and an alkylphenol
11471-5 (see note b) Rosin, polymer with an alkylphenol, bisphenol A, formaldehyde and glycerol
11472-6 (see note b) Rosin, maleated, polymer with a carbonyl compound, calcium, magnesium and zinc salts
11475-0 (see note b) Fatty acids, polymerized, reaction products with diethylenetriamine and tall-oil fatty acids
11512-1 (see note b) Phenol, 4,4′-(methylethylidene)bis-, polymer with (chloromethyl)oxirane, methyloxirane, and combined [oxy(methyl-1,2-ethanediyl)]
11513-2 (see note b) Reaction product of alkylphenol, formaldehyde, monoethanolamine, ethylene oxide and propylene oxide
11588-5 (see note b) Reaction product of: (4,4′-(1methylethylidene)bisphenol polymer with substituted methyl(oxirane) and 5-amino-1,3,3 trimethyl cyclohexane methanamine and N,N-bis(aminoethyl)-1,2-ethanediamine
11589-6 (see note b) Reaction product of: 4,4′-(1-Methyethylidene)bisphenol polymer with substituted methyl(oxirane) and 5-amino-1,3,3-trimethyl cyclohexane methanamine and 2,2,4 (or 2,4,4)trimethyl-1,6-hexanediamine

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DEPARTMENT OF THE ENVIRONMENT

DEPARTMENT OF HEALTH

CANADIAN ENVIRONMENTAL PROTECTION ACT, 1999

Announcement of planned actions to assess and manage, where warranted, the risks posed by certain substances to the health of Canadians and the environment

The actions, annexed hereby, outline how Health Canada and Environment and Climate Change Canada will address certain substances to reduce related human health and environmental risks.

CATHERINE MCKENNA
Minister of the Environment

JANE PHILPOTT
Minister of Health

ANNEX

Activities Under the Chemicals Management Plan Moving Forward

Under the Chemicals Management Plan (CMP), the Minister of the Environment and Climate Change and the Minister of Health (the ministers) will take multiple actions to protect the health of Canadians and the environment.

1. Background and rationale for action

The ministers take actions to protect human health and the environment pursuant to the CMP under several acts. This notice focuses primarily on actions that they will take under the Canadian Environmental Protection Act, 1999 (CEPA). As appropriate, however, actions are also taken under the Canada Consumer Product Safety Act (CCPSA), the Pest Control Products Act (PCPA) and the Food and Drugs Act (FDA). For details on actions taken under these acts, please refer to the following Web site: http://www.chemicalsubstanceschimiques.gc.ca/plan/plan-eng.php.

Since its inception, the CMP has represented an integrated, government-wide approach to the assessment and management of chemicals and other substances and has endeavoured to provide business certainty and public confidence through a predictable, science-based regulatory regime. To date, the CMP has assessed approximately 2 750 substances, found 363 substances that present risks to human health or the environment, and has put in place 78 instruments to manage these risks. The many initiatives of the CMP to date include the Challenge Initiative, the Substance Groupings Initiative, the Domestic Substances List (DSL) Inventory Updates, the rapid screening of substances of lower concern, as well as restrictions on the reintroduction or new uses of certain substances. The program supports these initiatives with ongoing risk assessment, risk management, information gathering, research, monitoring and surveillance, stakeholder engagement, public outreach, and international collaboration activities.

The current phase of the CMP began in April 2016. It includes, among other things, steps to address the remaining 1 550 priority substances out of the original 4 300 substances identified as priorities during the categorization exercise. It also includes the ongoing development of risk management actions for additional substances found to present risks that need to be prevented. Addressing these remaining priority substances in Canada supports the global goal of achieving the sound management of chemicals throughout their life cycle by 2020 — a goal that strives to ensure that chemicals are produced and used in ways that minimize significant adverse impacts on human health and the environment.

In order to support informed decision making, the next Inventory Update (IU), planned for fall 2016, will collect information on the commercial status and on exposures for a subset of CMP substances. Other information gathering and research and monitoring activities will also be undertaken to support evidence-based decision making.

This notice also covers

Engagement and outreach activities will remain important elements of the program.

2. Approach

This initiative retains features of the previous approach of the CMP that were found to be highly effective, such as predictable timelines and effective stakeholder engagement. Building on approaches used previously in the CMP, ongoing assessment activities will address substances or groups of substances using assessment approaches that are “fit-for-purpose.” Such tailoring of assessment approaches will help to focus efforts on the substances of greatest concern and will help make the engagement of stakeholders strategic and targeted. The approaches that may be applied are outlined in the Risk Assessment Toolbox at http:// www.chemicalsubstanceschimiques.gc.ca/fact-fait/ra-tool-outils-er-eng.php.

Management of substance risks will continue to involve the selection and application of tools that are most likely to achieve relevant health and environmental objectives while taking into account socio-economic and other considerations, including the relevant international context.

Canada will continue to participate in international chemical forums in order to ensure that issues and risks that are global in nature can be addressed effectively, and to influence the global agenda that reinforces domestic efforts.

3. Scope

This notice covers the component of the CMP that focuses on the remaining approximately 1 550 substances identified as priorities for further action by the categorization exercise completed in 2006, plus a limited number of additional substances identified as priorities based on new information received since that date. A list of the substances covered under this notice is found at http://www.ec.gc.ca/ese-ees/default.asp?lang=En&n=2A33EEC9-1 and includes information on their structural or functional groups. A two-year work plan for substance assessments will be released and updated regularly, in order to provide advance notice of timelines for each assessment. The substance assessment publication plan for the next two years can be found at http://www.ec.gc.ca/ese-ees/default.asp?lang=En&n=2D9B4BD2-1.

This phase of the program also includes the ongoing development and implementation of risk management instruments. This work will include activities to measure and report on the effectiveness of risk management actions. A two-year rolling schedule of risk management activities and consultation opportunities can be found at http://www.ec.gc.ca/ese-ees/default.asp?lang=En&n=8727ECCE-1. It will be updated regularly.

4. Planned actions

The ministers will take various actions to protect the health of Canadians and the environment from the potential risks associated with multiple substances. These actions may include, where warranted, information gathering, risk assessment, risk management, research and monitoring, stakeholder engagement, and public outreach. Manufacturers, importers and users of substances will continue to be expected to provide information to support risk assessment and risk management.

Specifically, the ministers plan to take the following actions to implement the next phase of the CMP under CEPA:

The ministers also plan to take the following actions under other legislation:

5. Stakeholder engagement

Stakeholder engagement will continue to be an important feature of the CMP. The ministers will continue to make information on chemical substances available publicly. The risk assessment work plan provides the start date for each assessment, and identifies the time frame within which information should be provided, as well as the expected publication date. The risk management work plan also provides information on upcoming stakeholder opportunities for engaging in risk management process activities.

Other opportunities for stakeholder engagement will include

Stakeholders are invited to submit relevant information on substances or indicate their interest in being engaged in discussions on particular substances or substance groups included in this notice of planned actions using the Declaration of Stakeholder Interest, available in the Single Window online reporting system at https://ec.ss.ec.gc.ca (select the “Chemicals Management Plan 3” Initiative). Stakeholders are also invited to subscribe to http://www.chemicalsubstanceschimiques.gc.ca/listserv/index-eng.php to be informed of information sessions and consultations.

6. Contact information

John Cooper
Acting Director General
Safe Environments Directorate
Health Canada

David Morin
Director General
Science and Risk Assessment Directorate
Environment and Climate Change Canada

Virginia Poter
Director General
Industrial Sectors, Chemicals and Waste Directorate
Environment and Climate Change Canada
Telephone: 1-800-567-1999 (in Canada) or 819-938-3232
Fax: 819-938-5212
Email: eccc.substances.eccc@canada.ca

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DEPARTMENT OF FINANCE

POOLED REGISTERED PENSION PLANS ACT

Effective date for the Multilateral Agreement respecting Pooled Registered Pension Plans and Voluntary Retirement Savings Plans

Notice is hereby given, pursuant to paragraph 6(4)(a) of the Pooled Registered Pension Plans Act, that the effective date for the Multilateral Agreement respecting Pooled Registered Pension Plans and Voluntary Retirement Savings Plans is June 15, 2016.

WILLIAM FRANCIS MORNEAU
Minister of Finance

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DEPARTMENT OF HEALTH

FOOD AND DRUGS ACT

PROTECTING CANADIANS FROM UNSAFE DRUGS ACT (VANESSA'S LAW)

Notice of intent to amend the Food and Drug Regulations and the Medical Devices Regulations to implement key authorities under Vanessa's Law

Notice is hereby given that Health Canada intends to develop and propose amendments to the Food and Drug Regulations and the Medical Devices Regulations as part of the implementation of Vanessa's Law.

Vanessa's Law received royal assent on November 6, 2014. It introduced amendments to the Food and Drugs Act (Act) that improve Health Canada's ability to collect post-market safety information, and take appropriate action when a serious risk to health is identified. These amendments promote better protection of patient health and safety, and increase consumer confidence in therapeutic products on the market.

Upon royal assent, many of the key authorities of Vanessa's Law came into force immediately. However, other key authorities cannot come into force until supporting regulations are established. The proposed regulations are to be developed in phases and prepublished in the Canada Gazette, Part I, beginning in fall 2016. The initial phase of the implementation would bring forward the following regulatory proposals.

1. Amending the Food and Drug Regulations to

2. Amending the Food and Drug Regulations and the Medical Devices Regulations to

These proposed amendments are intended to improve the effectiveness of recalls in Canada and to strengthen voluntary recall requirements to minimize the exposure of Canadians to defective or unsafe drugs and medical devices. The amendments would also address recommendations in the independent investigators' Final Report — Review of Health Canada's Actions in the Recall of Alysena™ 28 (http://www.hc-sc.gc.ca/ahc-asc/pubs/hpfb-dgpsa/ 2013-alysena-recall-rappel/index-eng.php) by further clarifying existing recall requirements to establish clear responsibilities for industry on the conduct of a recall.

The proposal to require a health care facility, other than hospitals, that distributes medical devices outside of its facility to obtain an establishment licence is intended to better manage the risk associated with the distribution of these devices.

Health Canada will continue to engage interested stakeholders on the development of the regulatory proposals supporting Vanessa's Law. However, there will be an opportunity for Canadians and all interested stakeholders to comment on the full proposals when these proposals are prepublished in the Canada Gazette, Part I.

Comments can be provided within 30 days of the date of this notice of intent to the Office of Legislative and Regulatory Modernization, Policy, Planning and International Affairs Directorate, Health Products and Food Branch, Health Canada, Holland Cross, Tower B, 5th Floor, Address Locator: 3105A, 1600 Scott Street, Ottawa, Ontario K1A 0K9, LRM_MLR_consultations@hc-sc.gc.ca (email).

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DEPARTMENT OF INDUSTRY

OFFICE OF THE REGISTRAR GENERAL

Appointments
Name and position Order in Council
Baker, John A. 2015-415
  • Social Sciences and Humanities Research Council
  
  • Member
  
Brassard, Manon 2016-450
  • Economic Development Agency of Canada for the Regions of Quebec
  
  • President
  
Clark, Monte 2016-416
  • Canadian Cultural Property Export Review Board
  
  • Member/Commissaire
  
Dupont, Serge 2016-453
  • Deputy Clerk of the Privy Council and Associate Secretary to the Cabinet to be concurrently Deputy Minister of Intergovernmental Affairs
  
Gaul, The Hon. Geoffrey R. J. 2016-441
  • Government of British Columbia
  
  • Administrator
  
  • June 9 and June 10, 2016
  
Hoy, The Hon. Alexandra H. 2016-421
  • Government of Ontario
  
  • Administrator
  
  • June 2 to June 4, 2016
  
Lucas, Stephen 2016-451
  • Senior Associate Deputy Minister of the Environment to be styled Senior Associate Deputy Minister (Climate Change) of Environment and Climate Change.
  
Maheu, Chantal 2016-452
  • Deputy Secretary to the Cabinet (Plans and Consultations), Privy Council Office
  
Morgan, Marta 2016-449
  • Deputy Minister of Citizenship and Immigration to be styled Deputy Minister of Immigration, Refugees and Citizenship
  
Sanderson, Robert 2016-418
  • Canada Deposit Insurance Corporation
  
  • Chairperson of the Board of Directors
  
Tai, Jackson 2016-417
  • Canada Pension Plan Investment Board
  
  • Director of the board of directors
  

June 7, 2016

DIANE BÉLANGER
Official Documents Registrar

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DEPARTMENT OF INDUSTRY

OFFICE OF THE REGISTRAR GENERAL

Appointments

Name and position

Instrument of Advice dated May 31, 2016

LeBlanc, The Hon. Dominic, P.C.

Leader of the Government in the House of Commons and Minister of Fisheries and Oceans to be styled Leader of the Government in the House of Commons and Minister of Fisheries, Oceans and the Canadian Coast Guard/Leader du gouvernement à la Chambre des communes et ministre des Pêches et des Océans devant porter le titre de leader du gouvernement à la Chambre des communes et ministre des Pêches, des Océans et de la Garde côtière canadienne

June 7, 2016

DIANE BÉLANGER
Official Documents Registrar

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DEPARTMENT OF TRANSPORT

CANADA TRANSPORTATION ACT

Levy on shipments of crude oil by rail

Pursuant to subsection 155.4(4) (see footnote 4) of the Canada Transportation Act (the Act), the amount of the levy in respect of payments into the Fund for Railway Accidents Involving Designated Goods required by subsection 155.7(1)* of the Act is $1.67 per tonne during the year commencing April 1, 2016.

May 12, 2016

MARC GARNEAU, P.C., M.P.
Minister of Transport

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